POA
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CAS Number:
357-57-3
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
394.5
Alternative Names:
2,3-dimethoxy-strychnidin-10-one, 2,3-dimethoxystrychnine
- Data sheet: View or download
- MSDS: View or download
Product Description:
An alkaloid with diverse biological activities; decreases synoviocyte proliferation and reduces paw and joint swelling in a rat model of adjuvant-induced arthritis when applied topically; reduces tumor incidence, number, and volume in a rat model of DMBA-induced mammary gland tumorigenesis at 4 and 8 mg/kg per day; prevents decreases in SOD, CAT, and GPX activity and increases the level of GSH in mammary tissues in a rat model of DMBA-induced mammary gland tumorigenesis at 4 and 8 mg/kg per day; allosterically enhances the effect of low, but not high, concentrations of acetylcholine at M1 muscarinic acetylcholine receptors
Storage Temperature:
-20°C