AS-605240
Catalogue number:
CAY10007707-5 mg
Supplier:
Size:
5 mg
Product is available in:
£73.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
648450-29-7
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
257.3
Alternative Names:
5-(6-quinoxalinylmethylene)-2,4-thiazolidinedione
- Data sheet: View or download
- MSDS: View or download
Product Description:
A potent inhibitor of PI3Kγ; inhibits human recombinant PI3Kγ, α, β, and δ in an ATP-competitive manner (IC50s = 8, 60, 270, and 300 nM, respectively); inhibits C5a-mediated phosphorylation of protein kinase B in RAW 264 cells (IC50 = 90 nM); suppresses joint inflammation in mouse models of rheumatoid arthritis; reduces RANTES-induced peritoneal neutrophil recruitment in a mouse model of leukocyte chemotaxis (ED50 = 9.1 mg/kg)
Storage Temperature:
-20°C
