Talfirastide
Catalogue number:
HY-12403-25mg
Supplier:
Size:
25 mg
Product is available in:
CAS Number:
51833-78-4
Purity:
99.91
Molecular Weight:
899.00
Alternative Names:
TXA127; Angiotensin (1-7); Ang-(1-7)
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Angiotensin 1-7 (Ang-(1-7)) is an endogenous heptapeptide from the renin-angiotensin system (RAS) with a cardioprotective role due to its anti-inflammatory and anti-fibrotic activities in cardiac cells. Angiotensin 1-7 inhibits purified canine ACE activity (IC50=0.65 µM). Angiotensin 1-7 acts as a local synergistic modulator of kinin-induced vasodilation by inhibiting ACE and releasing nitric oxide. Angiotensin 1-7 blocks Ang II-induced smooth muscle cell proliferation and hypertrophy and shows antiangiogenic and growth-inhibitory effects on the endothelium. Angiotensin 1-7 shows anti-inflammatory activity [1][2][3].
