Mevastatin
Catalogue number:
CAY10010340-50 mg
Supplier:
Size:
50 mg
Product is available in:
£102.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
73573-88-3
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
390.5
Alternative Names:
2s-methyl-(1s,2,3,7s,8s,8ar)-hexahydro-7-methyl-8-[2-[(2r,4r)-tetrahydro-4-hydroxy-6-oxo-2-h-pyran-2-yl]ethyl]-1-naphthalenyl ester-butanoic acid, compactin, cs 500, l-637,312, ml 236b, nsc 281245, statin i
- Data sheet: View or download
- MSDS: View or download
Product Description:
An HMG-CoA reductase inhibitor (Ki = 0.1 µM); inhibits cholesterogenesis in the liver and ileum of normolipidemic rats, as well as enhances suppression of cholesterogenesis in cholesterol-fed rats or rats administered cholestyramine at 50 mg/kg; suppresses TNF-induced NF-κB activation (IC50 = ~17 µM) and potentiates apoptosis in human myeloid leukemia cells; suppresses induced ferroptosis in HT-1080 cells
Storage Temperature:
-20°C
