This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
9012-63-9
Purity:
96
Alternative Names:
Choleragen
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Cholera toxin (Choleragen), an AB(5)-subunit toxin, enters host cells by binding the ganglioside GM1 at the plasma membrane (PM) and travels retrograde through the trans-Golgi Network into the endoplasmic reticulum (ER)[1]. Choleragen activates adenylate cyclase by catalyzing ADP-ribosylation of Gs alpha, the stimulatory guanine nucleotide-binding protein[2].
Storage Temperature:
Store at 4°C, do not freeze