AG-126
Catalogue number:
CAY13297-10 mg
Supplier:
Size:
10 mg
Product is available in:
£200.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
118409-62-4
Purity:
≥95%
Formulation:
A crystalline solid
Molecular Weight:
215.2
Alternative Names:
2-[(3-hydroxy-4-nitrophenyl)methylene]-propanedinitrile, tyrphostin ag-126
- Data sheet: View or download
- MSDS: View or download
Product Description:
A tyrphostin that is a poor inhibitor of EGFRK (IC50 = 450 µM) and PDGFRK (IC50 > 100 µM) which has been found to inhibit the phosphorylation of ERK1 and ERK2 at 25-50 µM; blocks the production of TNF-α, attenuating signaling through NF-κB, the induced expression of COX-2 and iNOS, and the inflammatory response
Storage Temperature:
-20°C