CGP 57380
Catalogue number:
CAY13322-5 mg
Supplier:
Size:
5 mg
Product is available in:
£142.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
522629-08-9
Purity:
≥95%
Formulation:
A crystalline solid
Molecular Weight:
244.2
Alternative Names:
n3-(4-fluorophenyl)-1h-pyrazolo[3,4-d]pyrimidine-3,4-diamine, mnk1 inhibitor
- Data sheet: View or download
- MSDS: View or download
Product Description:
A selective inhibitor of MNK1 in vitro (IC50 = 2.2 µM), with no inhibitory activity against p38, JNK1, ERK1/2, PKC, or Src-like kinases; blocks the phosphorylation of eIF4E in response to TNF-α, arsenite, anisomycin, PMA, or fetal calf serum in 293 cells (IC50 = 3 µM)
Storage Temperature:
-20°C