LY364947
Catalogue number:
CAY13341-5 mg
Supplier:
Size:
5 mg
Product is available in:
£120.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
396129-53-6
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
272.3
Alternative Names:
4-[3-(2-pyridinyl)-1h-pyrazol-4-yl]-quinoline, hts 466284, tgf-β ri kinase inhibitor
- Data sheet: View or download
- MSDS: View or download
Product Description:
A selective inhibitor of TGF-β RI, with an IC50 value of 59 nM; poorly inhibits TGF-β RII (IC50 = 400 nM), p38 MAPK (IC50 = 740 nM), and MLK7 (IC50 = 1,400 nM); inhibits TGF-β-induced cell growth (IC50 = 89 nM) and Smad phosphorylation
Storage Temperature:
-20°C
