Lys05 (hydrochloride)
Catalogue number:
CAY27334-10 mg
Supplier:
Size:
10 mg
Product is available in:
£130.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1391426-24-6
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
549.8
Alternative Names:
n2-(7-chloro-4-quinolinyl)-n1-[2-[(7-chloro-4-quinolinyl)amino]ethyl]-n1-methyl-1,2-ethanediamine, trihydrochloride, lys01
- Data sheet: View or download
- MSDS: View or download
Product Description:
An inhibitor of autophagy; induces p62 accumulation and increases the ratio of LC3-II to LC3-I in C8161 melanoma cells in a concentration-dependent manner; increases the number of autophagic vesicles per cell in tumors in a C8161 mouse xenograft model and reduces tumor volume and growth in a 1205Lu melanoma mouse xenograft model at 76 mg/kg; reduces tumor growth rate, volume, and weight in an HT-29 colon cancer mouse xenograft model at ≥10 mg/kg but increases bowel thickness and obstruction at 80 mg/kg
Storage Temperature:
-20°C
