HhAntag
Catalogue number:
CAY28296-10 mg
Supplier:
Size:
10 mg
Product is available in:
£278.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
496794-70-8
Purity:
≥95%
Formulation:
A crystalline solid
Molecular Weight:
450.9
Alternative Names:
n-[4-chloro-3-[6-(dimethylamino)-1h-benzimidazol-2-yl]phenyl]-3,5-dimethoxy-benzamide
- Data sheet: View or download
- MSDS: View or download
Product Description:
A hedgehog pathway inhibitor (EC50 = 0.4 µM for Shh signaling in a reporter assay); inhibits proliferation of GNP cells from 0.1 nM to 25 µM; suppresses Gli1 mRNA levels and increases tumor cell death in a mouse model of Ptc1+/-p53-/- medulloblastoma at 20 and 100 mg/kg; blocks basal and bone morphogenic protein 2-induced chondrogenesis in micromass cultures of mouse limb mesenchymal cells
Storage Temperature:
-20°C
