CRT0066854
Catalogue number:
CAY28463-1 mg
Supplier:
Size:
1 mg
Product is available in:
£64.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1438881-19-6
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
415.6
Alternative Names:
(2s)-3-phenyl-n1-[5,6,7,8-tetrahydro-2-(4-pyridinyl)[1]benzothieno[2,3-d]pyrimidin-4-yl]-1,2-propanediamine
- Data sheet: View or download
- MSDS: View or download
Product Description:
A PKCι and PKCζ inhibitor (IC50s = 132 and 639 nM, respectively); an inhibitor of ROCK2 (IC50 = 620 nM); is selective for PKCι, PKCζ, and ROCK2 over typical PKCs and 98 other kinases in a panel at 1 µM; decreases viability of A549 lung carcinoma cells (IC50 = 3.47 µM); decreases colony formation in HeLa cells by 65% at 1 µM; impairs lumen formation in MDCK cells in a Matrigel™ assay and migration of NRK-49F cells in a wound assay
Storage Temperature:
-20°C
