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Cellular Autophagy ELISA Kit (LC3-II Quantitation)

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48 assays _$$_
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£653.00 Estimated delivery Wed 28 Aug
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Cellular Autophagy ELISA Kit (LC3-II Quantitation) - 48 assays

Storage Temperature:

Upon receipt, store the Anti-LC3 Antibody and Secondary Antibody at -20°C. Store all other component

Processing of LC3. During autophagy, pro
Processing of LC3. During autophagy, pro-LC3 undergoes C-terminal proteolysis to form LC3-I (Cytosolic). LC3-I protein conjugates to phosphatidylethanolamine (PE) and translocates to the autophagosomal membrane (LC3-II). A selective permeabilization procedure is utilized to remove cytosolic pro-LC3 /LC3-I and retain autophagosome-bound LC3-II. LC3-II is used as a specific marker of autophagy.
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