This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
10238-21-8
Purity:
99.7
Molecular Weight:
494
Alternative Names:
Glyburide
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Glibenclamide (Glyburide) is an orally active ATP-sensitive K+ channel (KATP) inhibitor and can be used for the research of diabetes and obesity[1]. Glibenclamide inhibits P-glycoprotein. Glibenclamide directly binds and blocks the SUR1 subunits of KATP and inhibits the cystic fibrosis transmembrane conductance regulator protein (CFTR)[3]. Glibenclamide interferes with mitochondrial bioenergetics by inducing changes on membrane ion permeability[4]. Glibenclamide can induce autophagy[5].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)
