VU0364770 (hydrochloride)
Catalogue number:
HY-100588A-5mg
Supplier:
Size:
5 mg _$$_
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1414842-70-8
Purity:
99.7
Molecular Weight:
269.13
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
VU0364770 hydrochloride is a selective and potent positive allosteric modulator (PAM) of mGlu4. VU0346770 hydrochloride exhibits EC50s of 290 nM and 1.1 µM at rat mGlu4 and human mGlu4 receptor, respectively. VU0364770 hydrochloride exhibits antagonist activity at mGlu5 with a potency of 17.9 µM and PAM activity at mGlu6 with a potency of 6.8 µM. VU0364770 hydrochloride also possesses activity at MAO with Ki values of 8.5 and 0.72 µM for human MAO-A and human MAO-B, respectively[1].
Storage Temperature:
4°C (Powder, sealed storage, away from moisture)
