This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
865311-47-3
Purity:
99.91
Molecular Formula:
C35H33FN6O3
Molecular Weight:
604.67
Alternative Names:
CX-3543
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Quarfloxin (CX-3543), a fluoroquinolone derivative with antineoplastic activity, targets and inhibits RNA pol I activity, with IC50 values in the nanomolar range in neuroblastoma cells. Quarfloxin disrupts the interaction between the nucleolin protein and a G-quadruplex DNA structure in the ribosomal DNA (rDNA) template[1].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)