This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2252395-44-9
Purity:
98.72
Molecular Formula:
C24H21N3O4
Molecular Weight:
415.44
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
J22352 is a PROTAC (proteolysis-targeting chimeras)-like and highly selective HDAC6 inhibitor with an IC50 value of 4.7 nM. J22352 promotes HDAC6 degradation and induces anticancer effects by inhibiting autophagy and eliciting the antitumor immune response in glioblastoma cancers, and leading to the restoration of host antitumor activity by reducing the immunosuppressive activity of PD-L1[1].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)
