CCR2-RA-[R]

Name: CCR2-RA-[R]
Brand: Cayman Chemical
SKU: CBSKU_100846620
Price: 767 GBP
Availability: InStock

Catalogue number:

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CAY28423-25 mg

Supplier:

Cayman Chemical

Size:

25 mg

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£767.00

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Estimated delivery Wed 24 Dec
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This product is for research use only and is not for human consumption or therapeutic use.

CAS Number:

512177-83-2

Purity:

≥95%

Formulation:

A crystalline solid

Molecular Formula:

C18H19ClFNO3

Molecular Weight:

351.799503

Alternative Names:

(5r)-4-acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy-2h-pyrrol-2-one

Product Description:

An allosteric antagonist of CCR2 (IC50 = 103 nM); inhibits [35S]GTPγS binding and β-arrestin recruitment induced by CCL2 in U2OS membranes and cells, respectively, expressing CCR2 (IC50s = 24 and 25 nM, respectively)