MI-2
Catalogue number:
CAY29218-25 mg
Supplier:
Size:
25 mg
Product is available in:
£467.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1271738-62-5
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
375.6
Alternative Names:
4-[4-(4,5-dihydro-5,5-dimethyl-2-thiazolyl)-1-piperazinyl]-6-propyl-thieno[2,3-d]pyrimidine
- Data sheet: View or download
- MSDS: View or download
Product Description:
An inhibitor of menin-MLL fusion protein interactions (IC50 = 446 nM); binds to menin (Kd = 158 nM) and inhibits the menin-MLL-AF9 interaction in HEK293 cells; inhibits growth of mouse BMCs expressing the Hoxa9 transformation-dependent MLL-AF9 (GI50 = 5 µM); inhibits the growth of MV4, KOPN-8, ML-2, and MonoMac6 MLL cells expressing MLL fusion proteins (GI50s = 9.5, 7.2, 8.7, and 18 µM, respectively)
Storage Temperature:
-20°C
