BMS 189961
Catalogue number:
CAY29380-5 mg
Supplier:
Size:
5 mg
Product is available in:
£203.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
185629-22-5
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
399.5
Alternative Names:
3-fluoro-4-[[2-hydroxy-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)acetyl]amino]benzoic acid, bms 961
- Data sheet: View or download
- MSDS: View or download
Product Description:
A RARγ agonist (EC50 = 30 nM in a transactivation assay); selective for RARγ over RARβ (EC50 = 1,000 nM in the same assay); decreases long bone growth and digit formation of isolated mouse embryonic limb buds in vitro at 0.01 and 0.1 µM; increases the skin expression of retinoid metabolism-related genes, including Rdh10, Crabp2, and Krt4, as well as epidermal barrier genes, including Spink5, Klk5, and Klk7 when applied topically to mice at 40 nmol
Storage Temperature:
-20°C
