(S)-CR8
Catalogue number:
CAY29985-25 mg
Supplier:
Size:
25 mg
Product is available in:
£754.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1084893-56-0
Purity:
≥98%
Formulation:
A solid
Molecular Weight:
431.5
Alternative Names:
(2s)-2-[[9-(1-methylethyl)-6-[[[4-(2-pyridinyl)phenyl]methyl]amino]-9h-purin-2-yl]amino]-1-butanol
- Data sheet: View or download
- MSDS: View or download
Product Description:
An inhibitor of cyclin-dependent kinases (IC50s = 0.15, 0.08, 0.06, 0.12, and 0.11 µM for Cdk1/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E, Cdk5/p25, and Cdk9/cyclin T, respectively); inhibits CK1δ/ε and DYRK1A (IC50s = 0.61 and 0.9 µM, respectively); reduces cell viability in human neuroblastoma cell lines, including SH-SY5Y, SK-N-AS, SK-N-BE, and IMR32 cells (IC50s = 0.43, 1.46, 0.13, and 0.14 µM, respectively)
Storage Temperature:
-20°C
