Calcitriol
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32222-06-3
≥97%
A crystalline solid
416.6
(1r,3s,5z)-4-methylene-5-[(2e)-2-[(1r,3as,7ar)-octahydro-1-[(1r)-5-hydroxy-1,5-dimethylhexyl]-7a-methyl-4h-inden-4-ylidene]ethylidene]-1,3-cyclohexanediol, 1,25-dihydroxy cholecalciferol, 1,25-dihydroxy vitamin d3, 1α,25-dihydroxy cholecalciferol, 1α,25-d
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- MSDS: View or download
An agonist of the vitamin D3 receptor and active metabolite of vitamin D3; binds to the vitamin D3 receptor (Kd = 16 pM) and induces differentiation of U937 cells (EC50 = 2,000 pM); induces cell cycle arrest at the S phase and apoptosis in primary adenomatous and hyperplastic human parathyroid cells at 10 nM; increases bone calcium mobilization in chicks on a low calcium diet at 0.65 nmol/animal; stimulates calcium absorption in the intestines in a chick model of rickets induced by a vitamin D3-deficient diet
-20°C
