Berger, B.W., Kulp, D.W., Span, L.M., DeGrado, J.L., Billings, P.C., Senes, A., Bennett, J.S. and DeGrado, W.F. (2010). Consensus motif for integrin transmembrane helix association. Proceedings of the National Academy of Sciences, [online] 107(2), pp.703–708. Available at: https://www.pnas.org/content/107/2/703 [Accessed 5 Mar. 2020].
Product usage
Cell type: Jurkat
Nucleic acid: Plasmid DNA
Cai, W., Du, A., Feng, K., Zhao, X., Qian, L., Ostrom, R.S. and Xu, C. (2013). Adenylyl Cyclase 6 Activation Negatively Regulates TLR4 Signaling through Lipid Raft–Mediated Endocytosis. The Journal of Immunology, [online] 191(12), pp.6093–6100. Available at: https://www.jimmunol.org/content/191/12/6093 [Accessed 5 Mar. 2020].
Product usage
Cell type: RAW 264.7
Nucleic acid: Plasmid DNA
Cantero-Recasens, G., Fandos, C., Rubio-Moscardo, F., Valverde, M.A. and Vicente, R. (2010). The asthma-associated ORMDL3 gene product regulates endoplasmic reticulum-mediated calcium signaling and cellular stress. Human Molecular Genetics, [online] 19(1), pp.111–121. Available at: https://academic.oup.com/hmg/article/19/1/111/599403 [Accessed 5 Mar. 2020].
Product usage
Cell type: Jurkat
Nucleic acid: Plasmid DNA
Carreras-Sureda, A., Cantero-Recasens, G., Rubio-Moscardo, F., Kiefer, K., Peinelt, C., Niemeyer, B.A., Valverde, M.A. and Vicente, R. (2013). ORMDL3 Modulates Store-Operated Calcium Entry and Lymphocyte Activation. [online] Human molecular genetics. Available at: https://pubmed.ncbi.nlm.nih.gov/23100328-ormdl3-modulates-store-operated-calcium-entry-and-lymphocyte-activation/ [Accessed 5 Mar. 2020].
Product usage
Cell type: Jurkat
Nucleic acid: Plasmid DNA
Carroll, P.A., Kenerson, H.L., Yeung, R.S. and Lagunoff, M. (2006). Latent Kaposi’s Sarcoma-Associated Herpesvirus Infection of Endothelial Cells Activates Hypoxia-Induced Factors. Journal of Virology, [online] 80(21), pp.10802–10812. Available at: https://jvi.asm.org/content/80/21/10802 [Accessed 5 Mar. 2020].
Product usage
Cell type: TIME
Nucleic acid: Plasmid DNA
Chen, G., Bhojani, M.S., Heaford, A.C., Chang, D.C., Laxman, B., Thomas, D.G., Griffin, L.B., Yu, J., Coppola, J.M., Giordano, T.J., Lin, L., Adams, D., Orringer, M.B., Ross, B.D., Beer, D.G. and Rehemtulla, A. (2005). Phosphorylated FADD induces NF-κB, perturbs cell cycle, and is associated with poor outcome in lung adenocarcinomas. Proceedings of the National Academy of Sciences, [online] 102(35), pp.12507–12512. Available at: https://www.pnas.org/content/102/35/12507 [Accessed 5 Mar. 2020].
Product usage
Cell type: Jurkat
Nucleic acid: Plasmid DNA
Chen, Q.-Y., Zhang, T., Pincus, S.H., Wu, S., Ricks, D., Liu, D., Sun, Z., Maclaren, N. and Lan, M.S. (2010). Human CD1D Gene Expression Is Regulated by LEF-1 through Distal Promoter Regulatory Elements. The Journal of Immunology. [online] Available at: https://www.jimmunol.org/content/early/2010/04/02/jimmunol.0901912 [Accessed 5 Mar. 2020].
Product usage
Cell type: Jurkat
Nucleic acid: Plasmid DNA
Chen, Y., Leal, A.D., Patel, S. and Gorski, D.H. (2007). The Homeobox Gene GAX Activates p21WAF1/CIP1 Expression in Vascular Endothelial Cells Through Direct Interaction With Upstream AT-rich Sequences. [online] The Journal of biological chemistry. Available at: https://pubmed.ncbi.nlm.nih.gov/17074759-the-homeobox-gene-gax-activates-p21waf1cip1-expression-in-vascular-endothelial-cells-through-direct-interaction-with-upstream-at-rich-sequences/ [Accessed 5 Mar. 2020].
Product usage
Cell type: HUVEC
Nucleic acid: Plasmid DNA
Fitzpatrick, G.V., Pugacheva, E.M., Shin, J.Y., Abdullaev, Z., Yang, Y., Khatod, K., Lobanenkov, V.V. and Higgins, M.J. (2007). Allele-specific Binding of CTCF to the Multipartite Imprinting Control Region KvDMR1. [online] Molecular and cellular biology. Available at: https://pubmed.ncbi.nlm.nih.gov/17242189-allele-specific-binding-of-ctcf-to-the-multipartite-imprinting-control-region-kvdmr1/ [Accessed 5 Mar. 2020].
Product usage
Cell type: Jurkat
Nucleic acid: Plasmid DNA
Gao, L., Uzun, Y., Gao, P., He, B., Ma, X., Wang, J., Han, S. and Tan, K. (2018). Identifying noncoding risk variants using disease-relevant gene regulatory networks. Nature Communications, [online] 9(1), pp.1–12. Available at: https://www.nature.com/articles/s41467-018-03133-y [Accessed 5 Mar. 2020].
Product usage
Cell type: Jurkat
Nucleic acid: Plasmid DNA
Gavrilin, M.A., Mitra, S., Seshadri, S., Nateri, J., Berhe, F., Hall, M.W. and Wewers, M.D. (2009). Pyrin Critical to Macrophage IL-1β Response to Francisella Challenge. The Journal of Immunology, [online] 182(12), pp.7982–7989. Available at: https://www.jimmunol.org/content/182/12/7982 [Accessed 5 Mar. 2020].
Product usage
Cell type: Jurkat
Nucleic acid: Plasmid DNA
Ge, Y., Schuster, M.B., Pundhir, S., Rapin, N., Bagger, F.O., Sidiropoulos, N., Hashem, N. and Porse, B.T. (2019). The splicing factor RBM25 controls MYC activity in acute myeloid leukemia. Nature Communications, [online] 10(1), pp.1–14. Available at: https://www.nature.com/articles/s41467-018-08076-y [Accessed 5 Mar. 2020].
Product usage
Cell type: U937
Nucleic acid: Plasmid DNA
Product usage
Cell type: Kasumi-1
Nucleic acid: Plasmid DNA
Product usage
Cell type: Bone marrow cell cultures (mouse, primary)
Nucleic acid: Plasmid DNA
Product usage
Cell type: Acute myeloid leukemia (AML)
Nucleic acid: Plasmid DNA
Giroux, M., Delisle, J.S., O’Brien, A., Hébert, M.J. and Perreault, C. (2010). T Cell Activation Leads to Protein Kinase C Theta-Dependent Inhibition of TGF-beta Signaling. [online] Journal of immunology (Baltimore, Md. : 1950). Available at: https://pubmed.ncbi.nlm.nih.gov/20592275-t-cell-activation-leads-to-protein-kinase-c-theta-dependent-inhibition-of-tgf-beta-signaling/ [Accessed 5 Mar. 2020].
Product usage
Cell type: Jurkat
Nucleic acid: Plasmid DNA
Gutierrez, K.D., Morris, V.A., Wu, D., Barcy, S. and Lagunoff, M. (2013). Ets-1 Is Required for the Activation of VEGFR3 During Latent Kaposi’s Sarcoma-Associated Herpesvirus Infection of Endothelial Cells. [online] Journal of virology. Available at: https://pubmed.ncbi.nlm.nih.gov/23552426-ets-1-is-required-for-the-activation-of-vegfr3-during-latent-kaposis-sarcoma-associated-herpesvirus-infection-of-endothelial-cells/ [Accessed 5 Mar. 2020].
Product usage
Cell type: TIME
Nucleic acid: Multiple plasmid DNAs
Henson, D. m., Chou, C., Sakurai, N. and Egawa, T. (2014). A Silencer-Proximal Intronic Region Is Required for Sustained CD4 Expression in Postselection Thymocytes. [online] Journal of immunology (Baltimore, Md. : 1950). Available at: https://pubmed.ncbi.nlm.nih.gov/24729613-a-silencer-proximal-intronic-region-is-required-for-sustained-cd4-expression-in-postselection-thymocytes/ [Accessed 5 Mar. 2020].
Product usage
Cell type: Jurkat
Nucleic acid: Plasmid DNA
Application: Reporter assays
Holowka, D., Thanapuasuwan, K. and Baird, B. (2018). Short chain ceramides disrupt immunoreceptor signaling by inhibiting segregation of Lo from Ld Plasma membrane components. Biology Open, [online] 7(9). Available at: https://bio.biologists.org/content/7/9/bio034702 [Accessed 5 Mar. 2020].
Product usage
Cell type: Jurkat
Nucleic acid: Plasmid DNA
Ilinskaya, A., Heidecker, G. and Derse, D. (2010). Opposing Effects of a Tyrosine-Based Sorting Motif and a PDZ-Binding Motif Regulate Human T-Lymphotropic Virus Type 1 Envelope Trafficking. Journal of Virology, [online] 84(14), pp.6995–7004. Available at: https://jvi.asm.org/content/84/14/6995 [Accessed 5 Mar. 2020].
Product usage
Cell type: Jurkat
Nucleic acid: Plasmid DNA
Jiang, G., Espeseth, A., Hazuda, D.J. and Margolis, D.M. (2007). c-Myc and Sp1 Contribute to Proviral Latency by Recruiting Histone Deacetylase 1 to the Human Immunodeficiency Virus Type 1 Promoter. Journal of Virology, [online] 81(20), pp.10914–10923. Available at: https://jvi.asm.org/content/81/20/10914.abstract [Accessed 5 Mar. 2020].
Product usage
Cell type: Jurkat
Nucleic acid: Plasmid DNA
Jiang, M., Zhang, S., Yang, Z., Lin, H., Zhu, J., Liu, L., Wang, W., Liu, S., Liu, W., Ma, Y., Zhang, L. and Cao, X. (2018). Self-Recognition of an Inducible Host lncRNA by RIG-I Feedback Restricts Innate Immune Response. Cell, [online] 173(4), pp.906–919.e13. Available at: https://www.sciencedirect.com/science/article/pii/S0092867418303969 [Accessed 5 Mar. 2020].
Product usage
Cell type: L929
Nucleic acid: Plasmid DNA
Kalantari, P., Narayan, V., Henderson, A.J. and Prabhu, K.S. (2009). 15-Deoxy-Δ12,14-prostaglandin J2inhibits HIV-1 transactivating protein, Tat, through covalent modification. The FASEB Journal, 23(8), pp.2366–2373. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2717765/ [Accessed 5 Mar. 2020].
Product usage
Cell type: U937
Nucleic acid: Plasmid DNA
Kalantari, P., Narayan, V., Natarajan, S.K., Muralidhar, K., Gandhi, U.H., Vunta, H., Henderson, A.J. and Prabhu, K.S. (2008). Thioredoxin reductase-1 Negatively Regulates HIV-1 Transactivating Protein Tat-dependent Transcription in Human Macrophages. [online] The Journal of biological chemistry. Available at: https://pubmed.ncbi.nlm.nih.gov/18835810-thioredoxin-reductase-1-negatively-regulates-hiv-1-transactivating-protein-tat-dependent-transcription-in-human-macrophages/ [Accessed 5 Mar. 2020].
Product usage
Cell type: U937
Nucleic acid: Plasmid DNA
Kawamura, R., Tabara, Y., Tsukada, A., Igase, M., Ohashi, J., Yamada, R., Takata, Y., Kawamoto, R., Saito, I., Onuma, H., Tanigawa, T., Yamada, K., Kato, N., Ohyagi, Y., Miki, T., Kohara, K. and Osawa, H. (2016). Genome-wide association study of plasma resistin levels identified rs1423096 and rs10401670 as possible functional variants in the Japanese population. Physiological Genomics, 48(11), pp.874–881. Available at: https://pubmed.ncbi.nlm.nih.gov/27664181-genome-wide-association-study-of-plasma-resistin-levels-identified-rs1423096-and-rs10401670-as-possible-functional-variants-in-the-japanese-population/ [Accessed 5 Mar. 2020].
Product usage
Cell type: THP-1
Nucleic acid: Multiple plasmid DNAs
Application: Transient transfection
Product usage
Cell type: THP-1
Nucleic acid: Multiple plasmid DNAs
Application: Reporter assays
Knudson, K.M., Pritzl, C.J., Saxena, V., Altman, A., Daniels, M.A. and Teixeiro, E. (2017). NFκB–Pim-1–Eomesodermin axis is critical for maintaining CD8 T-cell memory quality. Proceedings of the National Academy of Sciences, [online] 114(9), pp.E1659–E1667. Available at: https://www.pnas.org/content/114/9/E1659 [Accessed 5 Mar. 2020].
Product usage
Cell type: T cells
Nucleic acid: Plasmid DNA
Application: Gene/protein expression
Product usage
Cell type: T cells
Nucleic acid: Plasmid DNA
Application: Reporter assays
Lange, U.C., Bialek, J.K., Walther, T. and Hauber, J. (2018). Pinpointing Recurrent Proviral Integration Sites in New Models for Latent HIV-1 Infection. [online] Virus research. Available at: https://pubmed.ncbi.nlm.nih.gov/29550509-pinpointing-recurrent-proviral-integration-sites-in-new-models-for-latent-hiv-1-infection/ [Accessed 5 Mar. 2020].
Product usage
Cell Type: Jurkat
Nucleic Acid: Plasmid DNA
Product usage
Cell Type: Jurkat
Nucleic Acid: CRISPR Guide RNA
Product usage
Cell Type: Jurkat
Nucleic Acid: Plasmid DNA
Lim, H.W., Kang, S.G., Ryu, J.K., Schilling, B., Fei, M., Lee, I.S., Kehasse, A., Shirakawa, K., Yokoyama, M., Schnölzer, M., Kasler, H.G., Kwon, H.-S., Gibson, B.W., Sato, H., Akassoglou, K., Xiao, C., Littman, D.R., Ott, M. and Verdin, E. (2015). SIRT1 deacetylates RORγt and enhances Th17 cell generation. The Journal of Experimental Medicine, [online] 212(5), pp.607–617. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419343/ [Accessed 5 Mar. 2020].
Product usage
Cell type: Jurkat
Nucleic acid: Plasmid DNA
Application: Reporter assays
Liu, L., Schwartz, B., Tsubota, Y., Raines, E., Kiyokawa, H., Yonekawa, K., Harlan, J.M. and Schnapp, L.M. (2008). Cyclin-Dependent Kinase Inhibitors Block Leukocyte Adhesion and Migration. Journal of immunology (Baltimore, Md. : 1950), [online] 180(3), pp.1808–1817. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623328/ [Accessed 5 Mar. 2020].
Product usage
Cell type: Jurkat
Nucleic acid: Plasmid DNA
Morris, V.A., Cummings, C.L., Korb, B., Boaglio, S. and Oehler, V.G. (2015). Deregulated KLF4 Expression in Myeloid Leukemias Alters Cell Proliferation and Differentiation Through MicroRNA and Gene Targets. [online] Molecular and cellular biology. Available at: https://pubmed.ncbi.nlm.nih.gov/26644403-deregulated-klf4-expression-in-myeloid-leukemias-alters-cell-proliferation-and-differentiation-through-microrna-and-gene-targets/ [Accessed 5 Mar. 2020].
Product usage
Cell type: THP-1
Nucleic acid: Plasmid DNA
Application: Reporter assays
Product usage
Cell type: KG1A
Nucleic acid: Plasmid DNA
Application: Reporter assays
Product usage
Cell type: Jurkat
Nucleic acid: Plasmid DNA
Application: Reporter assays
Patel, S., Leal, A.D. and Gorski, D.H. (2005). The Homeobox Gene Gax Inhibits Angiogenesis Through Inhibition of Nuclear factor-kappaB-dependent Endothelial Cell Gene Expression. [online] Cancer research. Available at: https://pubmed.ncbi.nlm.nih.gov/15735029-the-homeobox-gene-gax-inhibits-angiogenesis-through-inhibition-of-nuclear-factor-kappab-dependent-endothelial-cell-gene-expression/ [Accessed 5 Mar. 2020].
Product usage
Cell type: HUVEC
Nucleic acid: Plasmid DNA
Punjabi, A.S., Carroll, P.A., Chen, L. and Lagunoff, M. (2007). Persistent Activation of STAT3 by Latent Kaposi’s Sarcoma-Associated Herpesvirus Infection of Endothelial Cells. Journal of Virology, [online] 81(5), pp.2449–2458. Available at: https://jvi.asm.org/content/81/5/2449 [Accessed 5 Mar. 2020].Product usage
Product usage
Cell type: TIME
Nucleic acid: Plasmid DNA
Tourian, L., Zhao, H. and Srikant, C.B. (2004). p38alpha, but Not p38beta, Inhibits the Phosphorylation and Presence of c-FLIPS in DISC to Potentiate Fas-mediated caspase-8 Activation and Type I Apoptotic Signaling. [online] Journal of cell science. Available at: https://pubmed.ncbi.nlm.nih.gov/15572410-p38alpha-but-not-p38beta-inhibits-the-phosphorylation-and-presence-of-c-flips-in-disc-to-potentiate-fas-mediated-caspase-8-activation-and-type-i-apoptotic-signaling/ [Accessed 5 Mar. 2020].
Product usage
Cell type: Jurkat
Nucleic acid: Plasmid DNA
Tripathy, M.K., McManamy, M.E., Burch, B.D., Archin, N.M. and Margolis, D.M. (2015). H3K27 Demethylation at the Proviral Promoter Sensitizes Latent HIV to the Effects of Vorinostat in Ex Vivo Cultures of Resting CD4+ T Cells. [online] Journal of virology. Available at: https://pubmed.ncbi.nlm.nih.gov/26041287-h3k27-demethylation-at-the-proviral-promoter-sensitizes-latent-hiv-to-the-effects-of-vorinostat-in-ex-vivo-cultures-of-resting-cd4-t-cells/ [Accessed 5 Mar. 2020].
Product usage
Cell type: 2D10
Nucleic acid: shRNA-encoding plasmid DNA
Application: Gene knockdown
Twizere, J.-C., Lefèbvre, L., Collete, D., Debacq, C., Urbain, P., Heremans, H., Jauniaux, J.-C., Burny, A., Willems, L. and Kettmann, R. (2005). The Homeobox Protein MSX2 Interacts with Tax Oncoproteins and Represses Their Transactivation Activity. Journal of Biological Chemistry, [online] 280(33), pp.29804–29811. Available at: https://www.jbc.org/content/280/33/29804.full [Accessed 5 Mar. 2020].
Product usage
Cell type: BL-3
Nucleic acid: Plasmid DNA
Product usage
Cell type: Jurkat
Nucleic acid: Plasmid DNA
Wang, Y., Huynh, W., Skokan, T.D., Lu, W., Weiss, A. and Vale, R.D. (2019). CRACR2a is a calcium-activated dynein adaptor protein that regulates endocytic traffic. Journal of Cell Biology, [online] 218(5), pp.1619–1633. Available at: https://rupress.org/jcb/article/218/5/1619/120891/CRACR2a-is-a-calcium-activated-dynein-adaptor [Accessed 5 Mar. 2020].
Product usage
Cell type: Jurkat
Nucleic acid: Plasmid DNA
Xu, L. and Komatsu, M. (2009). Promoter Cloning and Characterization of the Anti-Vascular Proliferation Gene, R-ras: Role of Ets- And Sp-binding Motifs. [online] The Journal of biological chemistry. Available at: https://pubmed.ncbi.nlm.nih.gov/19011236-promoter-cloning-and-characterization-of-the-anti-vascular-proliferation-gene-r-ras-role-of-ets-and-sp-binding-motifs/ [Accessed 5 Mar. 2020].
Product usage
Cell type: CASMC
Nucleic acid: Plasmid DNA
Zhao, S., Gong, Z., Du, X., Tian, C., Wang, L., Zhou, J., Xu, C., Chen, Y., Cai, W. and Wu, J. (2018). Deoxycholic Acid-Mediated Sphingosine-1-Phosphate Receptor 2 Signaling Exacerbates DSS-Induced Colitis Through Promoting Cathepsin B Release. [online] Journal of immunology research. Available at: https://pubmed.ncbi.nlm.nih.gov/29854830-deoxycholic-acid-mediated-sphingosine-1-phosphate-receptor-2-signaling-exacerbates-dss-induced-colitis-through-promoting-cathepsin-b-release/ [Accessed 5 Mar. 2020].
Product usage
Cell type: J774A.1
Nucleic acid: siRNA
Zhiyong, Y.E. and Yunn-Hwen, G. (2007). Flagellin Contamination of Recombinant Heat Shock Protein 70 Is Responsible for Its Activity on T Cells. Journal of Biological Chemistry, [online] 282(7), pp.4479–4484. Available at: https://www.jbc.org/content/282/7/4479 [Accessed 5 Mar. 2020].
Product usage
Cell type: Jurkat
Nucleic acid: Plasmid DNA