Pexidartinib (hydrochloride)
Catalogue number:
HY-16749A-1g
Supplier:
Size:
1 g _$$_
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2040295-03-0
Purity:
99.89
Molecular Formula:
C20H16Cl2F3N5
Molecular Weight:
454.28
Alternative Names:
PLX-3397 (hydrochloride)
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Pexidartinib hydrochloride (PLX-3397 hydrochloride) is a potent, orally active, selective, and ATP-competitive colony stimulating factor 1 receptor (CSF1R or M-CSFR) and c-Kit inhibitor, with IC50s of 20 and 10 nM, respectively. Pexidartinib hydrochloride exhibits 10- to 100-fold selectivity for c-Kit and CSF1R over other related kinases. Pexidartinib hydrochloride induces cell apoptosis and has anti-cancer activity[1].
Storage Temperature:
4°C (Powder, sealed storage, away from moisture)