This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2244614-14-8
Purity:
99.71
Molecular Weight:
453.55
Alternative Names:
BTRX-335140; CYM-53093
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Navacaprant (BTRX-335140) is a selective and orally active κ opioid receptor (KOR) antagonist, has antagonist activity for κOR, µOR and δOR with IC50 values of 0.8 nM, 110 nM, and 6500 nM, respectively. Navacaprant endows with favorable in vitro ADMET and in vivo pharmacokinetic profiles and medication-like duration of action in rats. Navacaprant distributes well into the CNS and can be used for the research of neuropathy[1].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)