Avatrombopag (hydrochloride)
Catalogue number:
HY-13463B-10mg
Supplier:
Size:
10 mg _$$_
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
570403-17-7
Purity:
98.53
Molecular Weight:
686.12
Alternative Names:
AKR-501 (hydrochloride); E5501 (hydrochloride); YM477 (hydrochloride)
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Avatrombopag (AKR-501) hydrochloride is an orally active, nonpeptide thrombopoietin (TPO) receptor agonist (EC50=3.3 nM). Avatrombopag hydrochloride mimics the biological activities of TPO. Avatrombopag hydrochloride increases platelet production by activating the intracellular signaling system, and promotes production of platelets and megakaryocytes from hemopoietic precursor cells. Avatrombopag hydrochloride is a substrate of cytochrome P450 (CYP) 2C9 and CYP3A[1][2][3].
Storage Temperature:
4°C (Powder, sealed storage, away from moisture)