Vercirnon (sodium)
Catalogue number:
HY-15724A-10mg
Supplier:
Size:
10 mg _$$_
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
886214-18-2
Purity:
99.13
Molecular Weight:
466.91
Alternative Names:
GSK-1605786 (sodium); CCX282-B (sodium); Traficet-EN (sodium)
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Vercirnon (GSK1605786A) sodium is an orally bioavailable, selective, and potent antagonist of CCR9. Vercirnon sodium inhibits CCR9-mediated Ca2+ mobilization and chemotaxis on Molt-4 cells with IC50 values of 5.4 and 3.4 nM, respectively. Vercirnon sodium is selective for CCR9 over CCR1-12 and CX3CR1-7 (IC50s>10 µM for all). Vercirnon sodium is an equipotent inhibitor of CCL25-directed chemotaxis of both splice forms of CCR9 (CCR9A and CCR9B) with IC50 values of 2.8 and 2.6 nM, respectively[1].
Storage Temperature:
4°C (Powder, stored under nitrogen)