This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
874119-56-9
Purity:
99.68
Molecular Formula:
C24H16Cl2F2N6O
Molecular Weight:
513.33
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
GSK-25 is a potent, selective and orally bioavailable ROCK1 inhibitor (IC50=7 nM). GSK-25 maintains good selectivity against a panel of 31 kinases (>100 fold), as well as RSK1 and p70S6K (RSK1: IC50=398 nM, p70S6K: IC50=1 µM). GSK-25 inhibits P450 profile (IC50s of 2.5, 5.2, 2.5 µM for CYP2C9, CYP2D6, CYP3A4, respectively)[1].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)