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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
790702-57-7
Purity:
≥98%
Formulation:
A solid
Molecular Weight:
394.5
Alternative Names:
5-[(dimethylamino)sulfonyl]-n-(5-methyl-2-thiazolyl)-2-(1-pyrrolidinyl)-benzamide, n-linked glycosylation inhibitor 1
- Data sheet: View or download
- MSDS: View or download
Product Description:
An OST inhibitor; binds to and stabilizes the STT3B catalytic subunit of OST in a CETSA; inhibits N-linked glycosylation in a reporter assay using D54 ER-LucT cells (IC50 = 1.1 µM); reduces glycosylation and membrane localization of EGFR in H3255 lung adenocarcinoma cells and inhibits proliferation of PC-9 and A549 NSCLC cells at 10 µM; inhibits dengue and Zika virus replication in HEK293 cells (EC50s = 0.85 and 2.2 µM, respectively); reduces viral RNA in HEK293 cells infected with West Nile virus or yellow fever virus
Storage Temperature:
-20°C