£239.00
Estimated delivery Fri 9 Aug
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1874276-76-2
Purity:
≥95%
Formulation:
A crystalline solid
Molecular Weight:
472.5
Alternative Names:
3-amino-n-[3-(4-amino-4-methyl-1-piperidinyl)-2-pyridinyl]-6-[3-(trifluoromethyl)-2-pyridinyl]-2-pyrazinecarboxamide
- Data sheet: View or download
- MSDS: View or download
Product Description:
A PKC inhibitor (IC50s = 1.9 and 0.4 nM for PKCα and PKCθ, respectively); selective for PKCα and PKCθ over GSK3β (IC50 = 3,100 nM); inhibits proliferation of TMD8 B cell lymphoma and 92.1 uveal melanoma cells (IC50s = 900 and 184 nM, respectively) but not SK-MEL-28 skin melanoma cells (IC50 = >10,000 nM)
Storage Temperature:
-20°C