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Adiphenine (hydrochloride)

Catalogue number:
CAY31124-25 g
Supplier:
Size:
25 g _$$_
Product is available in:
  • UK
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£109.00 Estimated delivery Fri 2 Aug
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

50-42-0

Purity:

≥98%

Formulation:

A crystalline solid

Molecular Weight:

347.9

Alternative Names:

α-phenyl-benzeneacetic acid, 2-(diethylamino)ethyl ester, monohydrochloride, nsc 129224, spasmolytin, trasentin

Product Description:

An anticholinergic agent; a nAChR antagonist (IC50s = 1.8, 3.7, and 6.3 µM for the α3β4, α4β2, and α4β4 subunit-containing receptors, respectively), as well as muscarinic acetylcholine receptors (Ki = 0.44 µM); inhibits ACh-induced contractions in isolated guinea pig ileum in a concentration-dependent manner; prevents tonic hindlimb extension in a mouse model of seizures induced by MES (ED50 = 62 mg/kg); protects against organophosphate-induced lethality in mice (PD50 = 3.3 mg/kg)

Storage Temperature:

-20°C

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