£283.00
Estimated delivery Tue 27 Aug
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
487051-12-7
Purity:
≥98%
Formulation:
A solid
Molecular Formula:
C29H32F2N2O2
Molecular Weight:
478.6
Alternative Names:
n-[3-[1-[[4-(3,4-difluorophenoxy)phenyl]methyl]-4-piperidinyl]-4-methylphenyl]-2-methyl-propanamide
- Data sheet: View or download
- MSDS: View or download
Product Description:
An antagonist of MCH1 (Ki = 2.2 nM for the recombinant rat receptor); selective for MHC1 over α1A-adrenergic and dopamine D2 receptors (Kis = 180 and 7,400 nM, respectively, for the recombinant human receptors); increases the time mice spend in the light side of the light/dark exploration test at 20 mg/kg; reduces food intake and body weight, as well as plasma levels of glucose, insulin, and triglycerides, in a mouse model of high-fat diet-induced obesity at 5 mg/kg in combination with rimonabant
Storage Temperature:
-20°C