BAN ORL 24 (hydrochloride)
Catalogue number:
CAY29485-1 mg
Supplier:
Size:
1 mg _$$_
Product is available in:
£95.00
Estimated delivery Fri 23 Aug
Shipping is calculated in checkout
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1401463-54-4
Purity:
≥95%
Formulation:
A solid
Molecular Formula:
C27H35N3O2 • 2HCl
Molecular Weight:
506.5
Alternative Names:
1-(phenylmethyl)-n-[3-(spiro[isobenzofuran-1(3h),4′-piperidin]-1′-yl)propyl]-2-pyrrolidinecarboxamide, dihydrochloride
- Data sheet: View or download
- MSDS: View or download
Product Description:
A NOP receptor antagonist (Ki = 0.24 nM in a radioligand binding assay using CHO cell membranes expressing the human receptor); selective for NOP receptors over µ-, δ-, and κ-opioid receptors (Kis = 0.19, 0.34, and >1 µM, respectively); reduces NOP-induced GTPγS binding (pA2 = 9.98) and calcium mobilization (KB = 0.93 nM) in CHO cells; inhibits electrically induced twitches in isolated mouse and rat vas deferens, as well as isolated guinea pig ileum, at 100 nM; reverses BPR1M97-induced thermal and mechanical antinociceptive activities in mice
Storage Temperature:
-20°C