BAN ORL 24 (hydrochloride)
Catalogue number:
CAY29485-10 mg
Supplier:
Size:
10 mg _$$_
Product is available in:
£682.00
Estimated delivery Fri 23 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1401463-54-4
Purity:
≥95%
Formulation:
A solid
Molecular Formula:
C27H35N3O2 • 2HCl
Molecular Weight:
506.5
Alternative Names:
1-(phenylmethyl)-n-[3-(spiro[isobenzofuran-1(3h),4′-piperidin]-1′-yl)propyl]-2-pyrrolidinecarboxamide, dihydrochloride
- Data sheet: View or download
- MSDS: View or download
Product Description:
A NOP receptor antagonist (Ki = 0.24 nM in a radioligand binding assay using CHO cell membranes expressing the human receptor); selective for NOP receptors over µ-, δ-, and κ-opioid receptors (Kis = 0.19, 0.34, and >1 µM, respectively); reduces NOP-induced GTPγS binding (pA2 = 9.98) and calcium mobilization (KB = 0.93 nM) in CHO cells; inhibits electrically induced twitches in isolated mouse and rat vas deferens, as well as isolated guinea pig ileum, at 100 nM; reverses BPR1M97-induced thermal and mechanical antinociceptive activities in mice
Storage Temperature:
-20°C