DB1976 (dihydrochloride)
Catalogue number:
HY-135797A-1ml
Supplier:
Size:
1 ml _$$_
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2369663-93-2
Purity:
98
Molecular Weight:
520.28
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
DB1976 dihydrochloride is a selenophene analog of DB270 and a potent and cell-permeable fully efficacious transcription factor PU.1 inhibitor. DB1976 dihydrochloride potently inhibits PU.1 binding (IC50 of 10 nM) and strongly inhibits the PU.1/DNA complex (with high DB1976-λB affinity, KD of 12 nM) in vitro. DB1976 dihydrochloride has apoptosis-inducing effect[1][2][3].
Storage Temperature:
4°C (Powder, sealed storage, away from moisture)