This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1394371-75-5
Purity:
98.02
Molecular Weight:
419.94
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
nAChR agonist 1 is a potent, brain-permeable, and orally efficacious positive allosteric modulator of α7 nicotinic acetylcholine receptor (α7 nAChR). nAChR agonist 1 has the EC50 of 0.32 µM in a Ca2+ mobilization assay (PNU-282987-induced, FLIPR based) in human IMR-32 neuroblastoma cells that endogenously express α7 nAChR. nAChR agonist 1 can be develpoped for the treatment of Alzheimer’s disease[1].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)