This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1253573-53-3
Purity:
99.38
Molecular Formula:
C22H28FN9O3S
Molecular Weight:
517.58
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
AMG 511 is a potent and orally available pan inhibitor of class I PI3Ks, with Kis of 4 nM, 6 nM, 2 nM and 1 nM for PI3Kα, β, δ and γ, respectively. AMG 511 significantly suppresses PI3K signaling that is indicated by p-Akt (Ser473) decrease. AMG 511 exhibits anti-tumor activity in mouse glioblastoma xenograft model[1].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)