Samuraciclib (hydrochloride dihydrate)
Catalogue number:
HY-103712B-1ml
Supplier:
Size:
1 ml _$$_
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
Purity:
99.08
Molecular Formula:
C22H30N6O.(2.5HCl).(2H2O)
Molecular Weight:
521.7
Alternative Names:
CT7001 (hydrochloride dihydrate); ICEC0942 (hydrochloride dihydrate)
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Samuraciclib (CT7001) hydrochloride hydrate is a potent, selective, ATP-competitive and orally active CDK7 inhibitor, with an IC50 of 41 nM. Samuraciclib hydrochloride hydrate displays 45-, 15-, 230- and 30-fold selectivity over CDK1, CDK2 (IC50 of 578 nM), CDK5 and CDK9, respectively. Samuraciclib hydrochloride hydrate inhibits the growth of breast cancer cell lines with GI50 values between 0.2-0.3 µM. Samuraciclib hydrochloride hydrate has anti-tumor effects[1][2].
Storage Temperature:
4°C (Powder, stored under nitrogen, away from moisture)