GW806742X (hydrochloride)
Catalogue number:
HY-112292A-1ml
Supplier:
Size:
1 ml _$$_
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
Purity:
98.77
Molecular Formula:
C25H23ClF3N7O4S
Molecular Weight:
610.01
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
GW806742X hydrochloride, an ATP mimetic and a potent MLKL (Mixed Lineage Kinase Domain-Like protein) inhibitor, binds the MLKL pseudokinase domain with a Kd of 9.3 µM. GW806742X hydrochloride has activity against VEGFR2 (IC50=2 nM). GW806742X hydrochloride retards MLKL membrane translocation and inhibits necroptosis[1][2].
Storage Temperature:
4°C (Powder, sealed storage, away from moisture)