This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1715025-32-3
Purity:
99.83
Molecular Formula:
C26H27BrF3N5O2
Molecular Weight:
578.42
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Rineterkib (compound B) is an orally available ERK1 and ERK2 inhibitor in the treatment of a proliferative disease characterized by activating mutations in the MAPK pathway. The activity is particularly related to the treatment of KRAS-mutant NSCLC, BRAF-mutant NSCLC, KRAS-mutant pancreatic cancer, KRAS-mutant colorectal cancer (CRC) and KRAS-mutant ovarian cancer. Rineterkib hydrochloride can also inhibit RAF[1][2].
Storage Temperature:
4°C (Powder, sealed storage, away from moisture and light)