This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2561413-77-0
Purity:
99.63
Molecular Formula:
C30H38N6O2
Molecular Weight:
514.66
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
WF-47-JS03 is a potent and selective RET kinase inhibitor with IC50s of 1.7 nM and 5.3 nM for KIF5B-RET transfected Ba/F3 cells and CCDC6-RET transfected LC-2/ad lung cancer cells, respectively. WF-47-JS03 demonstrates >500-fold selectivity against kinase insert domain receptor (KDR). Effective brain penetration[1].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)