This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2408842-51-1
Purity:
98.71
Molecular Formula:
C30H31FN4O3
Molecular Weight:
514.59
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
WDR5-IN-1 is a potent and selective WD repeat domain 5 (WDR5) inhibitor, with a Kd of <0.02 nM. WDR5-IN-1 inhibits MLL1 histone methyltransferase (HMT) activity with an IC50 of 2.2 nM. WDR5-IN-1 diminishes MYC recruitment at WDR5-displaced genes and exhibits potent anti-proliferative effects in CHP-134 (neuroblastoma) and Ramos (Burkitt’s lymphoma) lines[1].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)