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VU0467485

Catalogue number:
HY-120184-5mg
Supplier:
Size:
5 mg _$$_
Product is available in:
  • UK
  • Ireland
  • Europe
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  • Rest of World
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

1451994-10-7

Purity:

99

Molecular Weight:

360.41

Alternative Names:

AZ13713945

Product Description:

VU0467485 (AZ13713945) is a potent, selective, and orally bioavailable muscarinic acetylcholine receptor 4 (M4) positive allosteric modulator (PAM). VU0467485 (AZ13713945) potentiates activity of ACh at M4 with EC50s of 26.6 nM and 78.8 nM at rat and human M4 receptors, respectively. VU0467485 (AZ13713945) shows selectivity for M4 over human and rat M1/2/3/5. VU0467485 (AZ13713945) displays moderate to high CNS penetration. VU0467485 (AZ13713945) has antipsychotic-like activity[1].

Storage Temperature:

-20°C, 3 years (Powder)

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