This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2160546-07-4
Purity:
99.93
Molecular Weight:
377.27
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
IACS-13909 is a selective, potent and orally active SHP2 allosteric inhibitor with an IC50 of 15.7 nM and a Kd of 32 nM. IACS-13909 is more selective for SHP2 than other phosphatases (including SHP1). IACS-13909 has antitumor activities and suppresses MAPK pathway signaling in receptor tyrosine kinases (RTK)-dependent cancers[1].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)