This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
958843-91-9
Purity:
98.99
Molecular Weight:
513.58
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
CMLD-2, an inhibitor of HuR-ARE interaction, competitively binds HuR protein disrupting its interaction with adenine-uridine rich elements (ARE)-containing mRNAs (Ki=350 nM). CMLD-2 induces apoptosis exhibits antitumor activity in different cancer cells as colon, pancreatic, thyroid and lung cancer cell lines. Hu antigen R (HuR) is an RNA binding protein, can regulate target mRNAs stability and translation[1][2].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)