This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2368900-35-8
Purity:
99.52
Molecular Weight:
559.61
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
CMLD012612 is an amidino-rocaglate containing a hydroxamate group and is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor. CMLD012612 inhibits cell translation and is cytotoxic to NIH/3T3 cells with an IC50 value of 2 nM. CMLD012612 inhibits eukaryotic translation initiation by modifying the behavior of the RNA helicase (eIF4A) and possesses potent anti-neoplastic activity[1].
Storage Temperature:
-20°C, 3 years (Powder)