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Sulthiame

Catalogue number:
CAY36271-1 mg
Supplier:
Size:
1 mg
Product is available in:
  • UK
  • Ireland
  • Europe
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  • Rest of World
£38.00 Estimated delivery Wed 7 Aug
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

61-56-3

Purity:

≥95%

Formulation:

A solid

Molecular Weight:

290.4

Alternative Names:

4-(tetrahydro-1,1-dioxido-2h-1,2-thiazin-2-yl)-benzenesulfonamide, sultiame

Product Description:

A pan-CA inhibitor (Kis = 6-1,540 nM for CAI, -II, and IV-XIV) and an anticonvulsant; selective for these CAs over CAIII (Ki = 630 µM); inhibits voltage-gated sodium currents in isolated guinea pig hippocampal CA1 neurons at 10 µg/ml; reduces 4-aminopyridine-induced epileptiform activity in guinea pig hippocampal slices at 2.5 mM; induces neuron degeneration in neonatal rats at 100-300 mg/kg, i.p.; decreases forelimb clonus duration in a rat model of partial epilepsy induced by amygdaloid kindling at 25-200 mg/kg

Storage Temperature:

-20°C

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