Abrocitinib
Catalogue number:
CAY34869-5 mg
Supplier:
Size:
5 mg
Product is available in:
£157.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1622902-68-4
Purity:
≥98%
Formulation:
A solid
Molecular Weight:
323.4
Alternative Names:
n-[cis-3-(methyl-7h-pyrrolo[2,3-d]pyrimidin-4-ylamino)cyclobutyl]-1-propanesulfonamide, pf-04965842
- Data sheet: View or download
- MSDS: View or download
Product Description:
A JAK1 inhibitor (IC50 = 0.029 µM); selective for JAK1 over JAK2, JAK3, and TYK2 (IC50s = 0.803, >10, and 1.253 µM, respectively) and a panel of 40 kinases at 1 µM; inhibits IFN-α-, IL-21-, or IL-27-induced phosphorylation of STAT3 (IC50s = 0.189, 0.511, and 0.271 µM, respectively) and IFN-γ-induced phosphorylation of STAT1 (IC50 = 0.163 µM) in isolated human whole blood; reduces paw edema in a rat model of adjuvant-induced arthritis at 1, 5, and 15 mg/kg
Storage Temperature:
-20°C