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BI-3406

Catalogue number:
CAY35261-5 mg
Supplier:
Size:
5 mg
Product is available in:
  • UK
  • Ireland
  • Europe
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£274.00 Estimated delivery Wed 7 Aug
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

2230836-55-0

Purity:

≥98%

Formulation:

A solid

Molecular Weight:

462.5

Alternative Names:

n-[(1r)-1-[3-amino-5-(trifluoromethyl)phenyl]ethyl]-7-methoxy-2-methyl-6-[[(3s)-tetrahydro-3-furanyl]oxy]-4-quinazolinamine

Product Description:

An inhibitor of the K-Ras-SOS1 protein-protein interaction (IC50 = 5 nM); selectively disrupts the protein-protein interaction between K-RasG12C or K-RasG12D with SOS1 over SOS2, and it is selective over 321 kinases in a panel at 10 µM but does inhibit PLK4, BMPR2, and LRRK2 activity by >50%

Storage Temperature:

-20°C

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