COH000
Catalogue number:
CAY34906-10 mg
Supplier:
Size:
10 mg
Product is available in:
£161.00
Estimated delivery Wed 7 Aug
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1534358-79-6
Purity:
≥98%
Formulation:
A solid
Molecular Weight:
419.5
Alternative Names:
(1r,4s)-1-[(1r)-2-(4-methylphenyl)-1-(phenylamino)ethyl]-7-oxabicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylic acid, 2,3-dimethyl ester
- Data sheet: View or download
- MSDS: View or download
Product Description:
An inhibitor of SUMO-activating enzyme (IC50 = 0.2 µM); selective for this enzyme over UAE and NAE at 10 µM; induces degradation of SAE2 in HCT116 human colon cancer cells; induces intratumoral apoptosis, decreases intratumoral c-Myc expression, and reduces tumor growth in an HCT116 mouse xenograft model at 10 mg/kg
Storage Temperature:
-20°C