Soticlestat
Catalogue number:
CAY34928-10 mg
Supplier:
Size:
10 mg
Product is available in:
£493.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1429505-03-2
Purity:
≥98%
Formulation:
A solid
Molecular Weight:
373.4
Alternative Names:
[2,4′-bipyridin]-3-yl[4-hydroxy-4-(phenylmethyl)-1-piperidinyl]-methanone, ov935, tak-935
- Data sheet: View or download
- MSDS: View or download
Product Description:
A cholesterol 24-hydroxylase/CYP46A1 inhibitor (IC50 = 0.0074 µM); selective for cholesterol 24-hydroxylase over CYP2C8, -2C9, -2D6, -3A4, -1A2, and 2C19 (IC50s = 62, 19, >100, 66, >100, and 14 µM, respectively); reduces seizure frequency and severity and improves survival in a model of Dravet syndrome induced by hyperthermia in Scn1a+/- mice at 0.02% in the diet
Storage Temperature:
-20°C